Acinetobacter baumannii (A. baumannii) is an important pathogen frequently associated with nosocomial epidemics around the world and considered in recent years as one of the most resistant pathogenic bacteria. Studies have shown that it is potentially resistant to several antibiotics, thus limiting current treatment options (Alouane et al., 2017). The World Health Organization (WHO) https://www.who.int/ published in 2017 its first list of priority pathogens resistant to antibiotics, listing the 12 families of bacteria most threatening to human health and classifying A. baumannii among the top pathogens, as the most critical bacteria. For this, research and development of new antibiotics is a priority. In Morocco, A. baumannii has become particularly problematic because of its remarkable ability to tolerate hostile environments, to colonize the human body, as well as its prevalence and resistance to antibiotics.
The Moroccan Sahara has a specific diversity, in the microorganism level, this diversity might be so interesting.
Bacteria in deserts have a high resistance to many environmental factors, this resistance might be due to some specific genomics variants or a way of expressions their genes, all those genomics and transcriptomics adaptations might be important in many biotechnology fields.
The Personal Genome Project is a vision and coalition of projects across the world dedicated to creating public genome, health, and trait data. Sharing data is critical to scientific progress, but has been hampered by traditional research practices. The PGP approach is to invite willing participants to publicly share their personal data for the greater good.
Helicobacter pylori(H. pylori) is a gram negative bacteria with 4 to 6 flagella. This human gastric pathogen, colonizes almost 50% of the world population . H. pylori is a major etiological agent for a wide range of gastric diseases such as gastritis, peptic ulcers, gastric carcinoma and mucosa-associated lymphoid tissue lymphoma . In morocco, the most common pathology resulting from H. pylori infection is chronic gastritis with a rate of 66%, the prevalence of primary resistances to clarithromycin is 29% and 40% to metronidazole
Mycobacterium tuberculosis is a human pathogen that has had a staggering global impact. Its origins are ancient. Spinal deformities typical of those resulting from M. tuberculosis disease have been found in human remains as far apart as Peru and Egypt and dating from at least 5000 BCE . The emergence of M. tuberculosis as a human pathogen is not well understood, but it has been plausibly suggested that the domestication of cattle facilitated close contact to humans, resulting in transmission with eventual evolution of M. bovis, the bovine tuberculosis strain.